Multivitamin Overdose & Heart Risks: “More Is Not Always Better” Dr Kamal Gupta, M.D (Med) DM (Cardio) FSCAI Additional Director, Cardiology, Fortis Hospital, Faridabad. Taking too many multivitamins can silently damage your heart. Excess fat-soluble vitamins (A, D, E, K) and minerals like calcium and iron are increasingly triggering atrial fibrillation, coronary calcification, and heart failure in Indian patients. • Vitamin D >100 nmol/L (from 60, 000 IU sachets) → 34% higher AFib risk • Extra calcium without K2 → accelerates artery blockage • Iron in men & post-menopausal women → doubles heart attack risk • High-dose Vitamin E → increases heart failure (HOPE trial) Real case: 48-year-old executive developed AFib after self-medicating weekly 60, 000 IU Vitamin D for 2 years. Remember Fat-soluble vitamins (A, D, E, K) accumulate — long-term mega-doses may be dangerous. Rule of thumb: Test → Don’t exceed 2000–4000 IU Vitamin D daily → Avoid routine calcium/iron pills → Choose food over supplements. Consult your Dr before starting any of the Gummies, powder supplements, vitamin supplements available at local chemists.