There has been a remarkable improvement in the treatment strategy of a hole in the heart most commonly atrial septal defect (ASD) over the last few decades. It is located between the upper two chambers of the heart. Indebted to the improvement in device technology and procedural techniques.The percutaneous closure of PFO and ASD is performed using a special closure device. The device is folded or attached on to a special catheter, similar to the catheter used during your catheterization. The catheter is inserted into a vein in the leg and advanced into the heart and through the defect. The device is slowly pushed out of the catheter allowing each side of the device to open up and cover each side of the hole (like a sandwich), closing the hole or defect.Transcatheter closure of ASD is currently accepted as the treatment of choice in most patients with secundum ASD. Recent generation devices enable easy and safe deployment of device with the properties of adequate flexibility, re-capturability and repositioning. Use of biocompatible materials with improved device design and refined equipment finish may promote re-endothelialization and reduce potential damage to nearby structures. Most of currently available devices show excellent efficacy and comparable outcome with its own advantages and disadvantages. In addition to improvement of device properties and performance, there has been distinct improvement in procedural technique from numerous experiences of device closure of ASD. Our Cardiac team has good experience in closing the ASD using percutaneous approach.